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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGO2
All Species:
11.52
Human Site:
S179
Identified Species:
21.11
UniProt:
Q9BRQ0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ0
NP_612157.1
406
41244
S179
G
Q
N
F
S
P
P
S
G
Q
M
M
P
G
P
Chimpanzee
Pan troglodytes
XP_525221
567
57276
S341
G
Q
N
F
S
P
P
S
G
Q
M
M
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001114666
405
41081
S179
G
Q
N
F
S
P
P
S
G
Q
M
M
P
G
P
Dog
Lupus familis
XP_547562
405
41099
G179
G
Q
N
F
S
P
P
G
G
Q
M
M
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0P5
417
45071
G173
T
Q
D
I
N
M
P
G
Q
H
F
R
Q
G
S
Rat
Rattus norvegicus
NP_001099917
405
41066
G179
G
Q
N
F
S
P
P
G
G
Q
M
I
P
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514326
407
43303
G161
G
Q
N
V
N
M
P
G
Q
H
F
R
P
N
P
Chicken
Gallus gallus
NP_001019862
418
44852
F157
G
P
H
D
S
P
G
F
G
N
Q
P
P
Y
S
Frog
Xenopus laevis
NP_001082328
389
41400
A160
G
Q
G
F
S
P
P
A
G
Q
M
M
Q
G
P
Zebra Danio
Brachydanio rerio
NP_001028283
571
56263
G299
G
K
N
F
G
G
P
G
G
G
P
P
V
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9W8
815
80474
N272
G
G
G
P
N
G
P
N
P
R
A
M
Q
G
S
Honey Bee
Apis mellifera
XP_394285
396
41911
S178
N
S
P
L
N
G
P
S
M
N
S
V
N
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791313
224
24117
T16
K
R
L
R
T
A
S
T
D
S
E
R
E
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.2
98.5
96.8
N.A.
36.4
96.3
N.A.
37.3
33.9
67.7
33.6
N.A.
21.3
23.3
N.A.
24.6
Protein Similarity:
100
71.2
98.7
97
N.A.
48.2
97
N.A.
48.1
44.2
74.8
39.5
N.A.
27.9
34.7
N.A.
35.4
P-Site Identity:
100
100
100
93.3
N.A.
20
86.6
N.A.
40
33.3
80
33.3
N.A.
26.6
20
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
93.3
N.A.
46.6
40
86.6
40
N.A.
46.6
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
54
0
0
0
8
0
0
16
0
0
0
0
% F
% Gly:
77
8
16
0
8
24
8
39
62
8
0
0
0
62
0
% G
% His:
0
0
8
0
0
0
0
0
0
16
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
8
0
47
47
0
0
0
% M
% Asn:
8
0
54
0
31
0
0
8
0
16
0
0
8
16
0
% N
% Pro:
0
8
8
8
0
54
85
0
8
0
8
16
54
8
62
% P
% Gln:
0
62
0
0
0
0
0
0
16
47
8
0
24
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
8
0
24
0
0
0
% R
% Ser:
0
8
0
0
54
0
8
31
0
8
8
0
0
8
31
% S
% Thr:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _